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Case report on COVID-19 and Vitamin C infusions

This report is regarding my older sister, 81 years of age, a former heavy smoker living in Denver, USA.   She quitted smoking about ten years ago, after having inserted two ”stents” in stenotic coronary arteries. On Friday March 6 , 2020 due to a newly developed 95% coronary artery stenosis my sister had an additional stent installed.   It should be noted, however, that she never previously presented signs of heart infarction on electrocardiograms (ECGs) or angina - her heart contractility was considered good.  On Saturday and Sunday, March 7th and 8th, my sister complained about severe postoperative fatigue, a never previously experienced loss of strength and extreme throat pain (later diagnosed as a COVID-19 infection).  Based on my sister’s schedule, it was considered that she had probably been infected with the virus 7 days earlier, before the coronary artery procedure, when she and her husband were in close contact with many people at a well-attended jazz musical event
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VITAMIN C, SEPSIS AND SEPSIS-INDUCED ARDS

Vitamin C - an antioxidant and a stress hormone Askorbic acid (Vitamin C) is synthesized from glucose in the liver. It is transported intracellularly by a protein called SVCT2 (Sodium-dependent Vitamin C Transporter 2), mainly to the suprarenal glands, the hypophysis, neurons, neutrophil leucocytes, lymfocytes and macrophages [81] where it is stored at concentrations one hundred times higher than in the plasma.  Almost all animals are capable of producing large amounts of Vitamin C due to the metabolite being the body’s most important antioxidant and stress hormone. It is a misconception that Vitamin C only functions as a vitamin. In fact, animal production of ascorbic acid is often significantly augmented at higher stress levels [82] . A frightened goat can easily double (2x) its production of ascorbic acid and under extreme conditions produce levels as high as 100 grams per day.   In order to understand the importance of the Vitamin C in sepsis and sepsis-induced
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About Vitamin C

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The greatest problem with using Vitamin C in the hospital is that most doctors view it solely as a vitamin - period. However, it has been demonstrated to be much more and by some doctor to be what the oil is for the motor of the car, an absolutely necessary lubricant.    The synthesis of Vitamin C in different animals  Most animals are capable of producing its own Vitamin C in the liver from the glucose molecule through four different enzyme reactions. Unfortunately, the fourth enzyme is missing in humans, why we are one of few species that can not produce our own Vitamin C. Other species, not capable of producing this vitamin are some primates, guinea-pig, and some rodents. The gene producing the enzyme, L-gulonolactone oxidas (i. e. Gulo), exists in the human genome, but is nonfunctioning due to a mutation. The pathway for synthesis is well known, i. e. 2-keto-L-gulonolactone to L-ascorbic acid [1, 2]. In view of the amount of Vitamin C given as guidelines for adul
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